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Clopidogrel (Plavix)
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Clopidogrel

Plavix is the medication of high quality which is taken in treatment of heart attacks and strokes by preventing blood clots. It is also taken to prevent other heart or blood vessels disorders. Plavix is acting by preventing blood clots.

Other names for this medication:
Algilis, Anclog, Anlet, Antiplaq, Antiplar, Apo clopidogrel, Areplex, Artevil, Atelit, Ateplax, Cirgrel, Clavix, Clocardigel, Clodian, Clognil, Clopact, Clopiboses, Clopicard, Clopid, Clopidix, Clopidogrelum, Clopidolut, Clopigamma, Clopigrel, Clopilet, Clopisan, Clopistad, Clopivas, Clopix, Clorel, Clorix, Clovexil, Clovix, Dapixol, Darxa, Dclot, Deplatt, Diloxol, Dopivix, Dorel, Duocover, Duoplavin, Expansia, Farcet, Flusan, Globel, Greligen, Grepid, Heart-free, Infartan, Iscover, Karum, Klopidogrel, Leril, Lopirel, Nabratin, Narutis, Nefazan, Niaclop, Noclog, Noklot, Odrel, Panagrel, Pidocar, Pidogrel, Pigrel, Pladex, Pladogrel, Plagerine, Plagril, Plagrin, Planor, Platfree, Plavigrel, Pleyar, Preclot, Ravalgen, Replet, Rokulan, Subarcan, Terotrom, Themigrel, Tisten, Troken, Trombex, Vaclo, Zillt, Zyllt

Similar Products:
Argatroban, Salagen, Arixtra, Persantine

 

Also known as:  Plavix.

Description

Plavix target is the treatment of heart attacks and strokes by preventing blood clots. It is also taken to prevent other heart or blood vessels disorders.

Plavix is acting by preventing blood clots. It is antiplatelet agents.

Plavix is also known as Clopidogrel, Clopitab, Caplor, Iscover, Clopilet, Ceruvin.

Generic name of Plavix is Clopidogrel.

Brand name of Plavix is Plavix.

Dosage

Take Plavix at the same time every day, with or without food.

Take Plavix tablets orally with water.

If you want to achieve most effective results do not stop taking Plavix suddenly.

Overdose

If you overdose Plavix and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Plavix overdosage: vomiting, abnormal bleeding or bruising, problems with breathing.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Clopidogrel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Plavix if you are allergic to Plavix components.

Do not take Plavix if you're pregnant or you plan to have a baby, or you are a nursing mother.

Be careful with Plavix if you suffer from or have a history of stroke, stomach ulcer or ulcerative colitis; liver or kidney disease, hemophilia.

Be careful with Plavix if you are taking such medicines as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs such as naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ibuprofen (Motrin, Advil), (Toradol), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), ketorolac mefenamic acid (Ponstel), meloxicam (Mobic) and the others), phenytoin (such as Dilantin); torsemide (such as Demadex); medication used to prevent blood clots (alteplase (such as Activase), anistreplase (such as Eminase), dipyridamole (such as Persantine), streptokinase (such as Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (such as Abbokinase); fluvastatin (such as Lescol); a blood thinner (warfarin (such as Coumadin), heparin, ardeparin (such as Normiflo), dalteparin (such as Fragmin), danaparoid (such as Orgaran), enoxaparin (such as Lovenox), or tinzaparin (such as Innohep); tamoxifen (such as Nolvadex); tolbutamide (such as Orinase).

It is not recommended to do sport while taking Plavix because it can cause bleeding or bruising injury.

If you are going to have a surgery you should stop taking Plavix for 5 days before the surgery.

Do not use potassium supplements or salt substitutes.

If you want to achieve most effective results without any side effects it is better to avoid alcohol.

Do not stop taking Plavix suddenly.

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A total of 43,159 clopidogrel users were identified. Among them, 15,415 (35.7%) received clopidogrel and a PPI concomitantly at any time during the study period, 3502 (8.1%) experienced a MCE, 7306 (17.1%) died, and a total of 9908 (22.8%) experienced the primary composite outcome (any MCE or all-cause mortality) during follow-up. The odds ratio (OR) for the primary composite outcome was 1.26 (95% confidence interval [CI]: 1.18-1.35). Secondary analyses indicated that elderly patients using clopidogrel and a PPI concomitantly were more likely to experience all-cause mortality (OR: 1.40; 95% CI: 1.29-1.53) as compared to those receiving clopidogrel only, but not MCEs (OR: 1.06; 95% CI: 0.95-1.18).

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We evaluated the relationship between plasma inflammation markers and clopidogrel resistance in patients after stent implantation. The plasma levels of C-reactive protein (CRP), P-selectin, platelet soluble CD40 ligand (sCD40L), interleukin 6 (IL-6) and platelet aggregation were measured in 352 patients undergoing percutaneous coronary intervention (PCI) at baseline and after 6 months. The plasma levels of CRP, P-selectin, sCD40L, IL-6 was higher in 65 (18.5%) patients with clopidogrel resistance than in those with normal responsiveness at 6 months after PCI. There was a significant positive correlation between soluble CD40L levels and platelet aggregation (r = .28, P < .05). Diabetes (DM) and sCD40L level were independent predictors for unresponsiveness after stent implantation according to stepwise multivariate analyses. The hazard ratio (HR) for sCD40L level was 3.02 (95% CI = 1.28 to 3.25; P = .036) and for DM 2.53 (95% CI = 1.28 to 6.55, P = .03). We conclude that sCD40L and DM may influence clopidogrel resistance.

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Platelet reactivity with prasugrel 60 mg LD added to clopidogrel 600 mg LD was not significantly different compared with prasugrel 60 mg LD alone in acute coronary syndrome patients undergoing percutaneous coronary intervention.

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Case-control study.

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To review the contemporary literature on optimal medical therapy after PCI.

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The risk of cardiovascular events among patients with atrial fibrillation is high. We evaluated whether irbesartan, an angiotensin-receptor blocker, would reduce this risk.

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one hundred patients who received clopidogrel within 5 days of OPCABG were prospectively enrolled. The primary end point was to compare post-operative bleeding and transfusion requirement in relation to the tertile distribution of the percentage of platelet inhibitory response to clopidogrel.

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Dysglycemia may influence the predictive value of CYP2C19 loss-of-function allele for clinical efficacy of antiplatelet drug, but the role of glycated albumin (GA) remains unclear Buy Prednisone Overnight Delivery in patients with stroke on antiplatelet drugs.

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This observational, longitudinal, prospective and continuous study included 307 patients aged over 75 Buy Tacrolimus years consecutively admitted for non-ST elevation ACS. They were divided into two groups, according to the approach adopted: Group A (n=91)--patients treated with an early invasive strategy; and Group B (n=216)--patients treated conservatively. The median clinical follow-up was 18 months.

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To evaluate mid-term clinical and angiographic results after using a self-expanding neurovascular stent and coils for the management of Prilosec Get You High broad-based intracranial aneurysms.

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Tapering vs. abrupt discontinuation of clopidogrel treatment results Can You Buy Elavil in significantly lower platelet aggregation values after 14 days from complete drug cessation. We found no evidence of a platelet rebound effect.

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Bleeding from the upper gastrointestinal tract is not frequent shortly after coronary angiography, but the related mortality is high. The most frequent source of bleeding are duodenal peptic lesions most likely Buy Dipyridamole caused by previous treatment by acetylsalicylic acid.

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The analysis indicates Buy Zoloft 100mg that clopidogrel is cost effective for the secondary prevention of atherothrombotic events in the Greek setting. These findings are in line with those reported in other European countries.